The 3IET pdb entry holds the crystal strucure of an antibody recognizing a unique tumor-specific glycopeptide antigen.
The following example demonstrates the identification of its Antigen Bidning Regions (ABRs) from both its the sequence and 3D structure.
Figures 1, 2, 3 and 4 show the results of running Paratome on the sequence and structure of the 3IET antibody. For further details regarding results interpretation, please see the tutorial.
NOTE: to run the demo (sequence or structure), press , confirm the prompted message and wait a few seconds till data upload ends and processing begins.
Example files: 3iet.fasta, 3iet.pdb.
Figure 1. Paratome ABRs identification - HTML results.
Figure 2. Paratome ABRs identification - Jmol viewer.
Figure 3. Paratome ABRs identification - text results (structure).
Figure 4. Paratome ABRs identification - text results (sequence).